Publications — TheLowLab

Publications

Andrew G Morrison, Raphaella Jackson, Paul S Freemont, Harry H Low (2026). An enhanced domestication method for uncultured bacteria. ISME Communications, ycag062, https://doi.org/10.1093/ismeco/ycag062 . Highlighted by the American Society For Microbiology TWiM podcast. Have a listen here!

Williams TA, Low HH (2025). The evolution and mechanism of bacterial and archaeal ESCRT-III-like systems. Current Opinion in Structural Biology. https://doi.org/10.1016/j.sbi.2025.103111

Michael Hohl, Emma J Banks, Max P Manley, Tung BK Le and Harry H Low (2024). Bidirectional pilus processing in the Tad pilus system motor CpaF. Nature Commun DOI: 10.1038/s41467-024-50280-6 15, 6635.

Souvik Naskar, Andrea Merino, Javier Espadas, Jayanti Singh, Aurelien Roux, Adai Colom, Harry H Low. Mechanism for Vipp1 spiral formation, ring biogenesis and membrane repair. Nature Structure and Molecular Biology https://doi.org/10.1038/s41594-024-01401-8 (2024).

Schlösser L, Sachse C, Low HH, Schneider D. Conserved structures of ESCRT-III superfamily members across domains of life. Trends Biochem Sci. Vol: 48, Pages 993-1004 (2023).

Tassinari, M., Rudzite, M., Filloux, A., Low HH. Assembly mechanism of a Tad secretion system secretin-pilotin complex. Nat Commun 14, 5643 (2023).

Jiwei Liu, Matteo Tassinari, Diorge P Souza, Souvik Naskar, Jeffrey K. Noel, Olga Bohuszewicz, Martin Buck, Tom A. Williams, Buzz Baum, Harry H Low (2021). Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodelling superfamily. Cell. Vol: 184, Pages 3660-3673.

Nasker S, Hohl M, Tassinari M, Low HH (2020). Structure and mechanism of the bacterial type II secretion system. Molecular Microbiology. Vol: 115, Pages: 412-424.

Chernyatina AA, Low HH (2019). Core architecture of a bacterial type II secretion system. Nature Communications. Vol: 10, Article number: 5437.

Liu J, Noel J, Low HH (2018). Structural basis for membrane tethering by a bacterial dynamin-like pair. Nature Communications. Vol: 9, Article number:3345.

Bohuszewicz O, Low HH (2018). Structure of a mitochondrial dynamin in the closed conformation. Nature Structural & Molecular Biology. Vol: 25, Pages: 722-731.

Antonny, B., Burd, C., De Camilli, P., Chen, E., Daumke, O., Faelber, K., Ford, M., Frolov, V., Frost, A., Hinshaw, J.E., Kirchhausen, T., Kozlov, M.M., Lenz, M., Low, H.H., McMahon, H.T., Merrifield, C., Pollard, T.D., Robinson, P., Roux, A., Schmid, S.L. (2016). Membrane fission by dynamin: what we know and what we need to know. Embo J. Vol: 35, Pages: 2270-2284. doi:10.15252/embj.201694613

Bohuszewicz O*, Liu J*, Low HH, 2016, Membrane remodelling in bacteria. Journal of Structural Biology. doi:10.1016/j.jsb.2016.05.010. *co-first author

Michie KA*, Boysen A*, Low HH*, Møller-Jensen J, Löwe J, 2014, LeoA, B and C from enterotoxigenic Escherichia coli (ETEC) are bacterial dynamins. PLoS ONE 9(9): e107211. doi:10.1371/journal.pone.0107211. *co-first author

Low HH*, Gubellini F*, Rivera-Calzada A, Braun N, Connery S, Dujeancourt A, Lu F, Redzej A, Fronzes R, Orlova EV, Waksman G, 2014, Structure of a Type IV secretion system. Nature. Vol: 508, Pages:550-553. *co-first author

Low HH, Löwe J, 2010, Dynamin architecture--from monomer to polymer. Curr Opin Struct Biol. Vol:20, Pages:791-798.

Low HH, Sachse C, Amos LA, Löwe J, 2009, Structure of a bacterial dynamin-like protein lipid tube provides a mechanism for assembly and membrane curving. Cell. Vol:139, Pages:1342-1352.

Low HH, Löwe J, 2006, A bacterial dynamin-like protein. Nature. Vol:444, Pages:766-769.

Low HH, Moncrieffe MC, Löwe J, 2004, The crystal structure of ZapA and its modulation of FtsZ polymerisation. Journal of Molecular Biology. Vol:341, Pages:839-852.